Overlooked Causes of Miscarriage

1. Low Vitamin Levels Nutritional deficiencies, particularly low levels of vitamin D, have been linked to recurrent pregnancy loss. Vitamin D plays a critical role in immune modulation and endometrial receptivity, both of which are essential for maintaining a healthy pregnancy. It influences the activity of immune cells such as T regulatory cells, which help prevent an overactive immune response that could harm early pregnancy. Additionally, vitamin D enhances endometrial receptivity by promoting the expression of implantation-related genes and supporting the vascular development of the endometrium. Without adequate levels, the body may struggle to support early implantation and fetal development. Research indicates that women with vitamin D deficiency may face increased difficulty in sustaining a pregnancy.

    

2. Gut Dysbiosis An imbalanced gut microbiome can lead to systemic inflammation and disrupt the delicate hormonal balance necessary for pregnancy. The gut microbiome varies throughout the gastrointestinal (GI) tract, influencing immune cell production such as secretory IgA. This antibody supports mucosal immunity and helps regulate inflammation. Disruptions in the gut microbiota can affect hormone production, including progesterone, and create an environment less conducive to pregnancy.

    

3. Vaginal Infections Conditions like bacterial vaginosis (BV) are often overlooked but can increase the risk of miscarriage. BV disrupts the normal vaginal flora, leading to inflammation and an environment that may hinder early pregnancy. Research has demonstrated a link between BV and infertility, emphasizing the importance of assessing and treating this condition.

    

4. Low Progesterone Often referred to as the "pregnancy hormone," progesterone is essential for maintaining the uterine lining and supporting the early stages of pregnancy. Low levels can result from not eating enough to support hormonal health. Inadequate caloric intake or nutrient deficiencies can impair progesterone production, making it difficult to sustain a pregnancy. Additionally, research has shown that sleep disturbances can reduce progesterone levels, highlighting the importance of restorative sleep. Progesterone and estrogen levels also influence the vaginal microbiome, with imbalances potentially contributing to an environment that supports conditions like BV.

    

5. Undiagnosed Autoimmune Conditions Autoimmune conditions such as antiphospholipid syndrome, Lupus (SLE) or Hashimoto's Thyroiditis can contribute to pregnancy loss by creating an inflammatory or hostile immune environment. These conditions are frequently undiagnosed until multiple miscarriages occur.

6.  Poor Sperm Health Male factors, such as high DNA fragmentation in sperm, play a significant role in miscarriage risk. DNA fragmentation can lead to poor embryo quality, even if fertilization occurs. High levels of DNA fragmentation are associated with impaired embryo development, disrupted blastocyst formation, and reduced implantation potential. This fragmentation compromises the integrity of genetic material critical for early fetal development and increases the likelihood of early pregnancy loss. Addressing male fertility with targeted nutrition and lifestyle changes is critical for improving outcomes.

• Nutritional Support: Ensuring adequate intake of vitamins and minerals through a diet rich in whole foods, including leafy greens, fatty fish, seeds, and legumes. Targeting specific deficiencies, like vitamin D, through diet and supplementation when necessary.

• Gut Health Restoration: Incorporating probiotics, fermented foods, and a diverse diet to support a healthy microbiome. Treating underlying infections with herbal therapies can also help to balance gut microbiome.

• Addressing Vaginal Infections: Using natural remedies, such as probiotics and antimicrobial herbs, under the guidance of a healthcare professional. Companies like Evvy offer vaginal microbiome testing.

• Hormone Balance: Supporting progesterone levels through lifestyle changes, stress reduction, and, if needed, bioidentical progesterone therapy.

• Reducing Toxin Exposure: Switching to non-toxic cleaning products, avoiding plastic containers, and prioritizing organic foods to minimize exposure to harmful chemicals.

• Male Fertility Support: Encouraging a nutrient-dense diet, stress reduction, and lifestyle changes to improve sperm quality.